If you like the tried and true, however, stick to retinol and tretinoin for now and re-examine the question in a couple of years when (hopefully) more research will be available. Pretty encouraging, though we are very much waiting for a study to confirm all this on real human beings.īottom line: We are really happy to see some innovation happening with retinoids, and we think Hydroxypinacolone Retinoate is a super promising rising star, but it’s not fully proven yet. If you are someone who likes to experiment and try out the newest things, grab your running shoes and try some HPR containing serum now (see product list below :)). however, HPR did not achieve gene transcription levels of ATRA (tretinoin)." But, a much higher dose might be tolerated from HPR and the highest dose of HPR out-performed tretinoin. The results are pretty encouraging showing that " HPR had greater levels of gene transcription than retinol and RP (RP) at the same concentrations. This formulation combines two forms of next-generation retinoid actives. This serum with a creamy texture is great for those looking for solutions for textural irregularities / signs of aging without the side effects associated with retinol. The formula continues to offer an emulsion of 2 of the same advanced retinoid complex. Regarding anti-aging, there is a pretty recent, Estee Lauder sponsored study that compared the in-vitro (not on real human beings but on skin models) collagen-boosting effectiveness of Hydroxypinacolone Retinoate, tretinoin, good old retinol and retinyl palmitate (RP). 10.50 Store & Pickup Availability Details Granactive Retinoid 2 Emulsion from The Ordinary is an emulsion of a next-generation form of retinoid. Both studies found the formulas effective but they contained other things too, so it's hard to judge how well HPR did. We found two Italian studies both examining the efficacy of HPR combined with other things (retinol in both cases, and papain in one of them) for the treatment of acne. But, before you do, you have to know that the info we have about HPR at the moment is mainly from the manufacturer, whose tests may or may not be accurate or properly designed (such as controlled, double-blind and conducted on an appropriate number of people).Īs HPR is pretty new there isn't that much independent research we could find yet. These results sound sooo promising that we don't blame you if you wanna run out right now and get an HPR formula to slather on your face. Also, there was a "dramatic reduction of lines and wrinkles" after applying 0.2% HPR around the eyes twice a day for 14 days. According to the manufacturer's tests, 24 hours of an occlusive patch with 0.5% HPR resulted in significantly lower irritation than 0.5% retinol. I like the fact that it's free of fragrance, alcohol and essential oils. Details: This retinoid has a milky texture and a faint smell that I can't describe very well. Non-irritating retinoid that is smooth, silky and easy to absorb. ![]() The big promise of HPR is that it's similarly active as retinoic acid (no conversion needed, remember) but without the irritation. Summary: This is one of the products of The Ordinary I've used the longest. Granactive Retinoid Emulsion (2019 formulation). It binds directly to the retinoid receptors of the skin cells to work its skincare magic. The Ordinary Granactive Retinoid 2 Squalane (2019 formulation). Other forms of retinoids have to be converted by our metabolic machinery to do something. If you've already read our description about retinol or retinyl palmitate, you know that the active ingredient our skin cells can interpret is retinoic acid. It's a so-called retinoic acid ester, meaning that it's directly related to retinoic acid. They will only cause your skin harm and worsen your condition.Rosmarinus Officinalis (Rosemary) Leaf Extract Which ingredients should you avoid with Textural Irregularities? Avoid products containing alcohol and fragrance like the plague. You will need all the moisture to help tackle rough skin I alternate using it with hyaluronic acid. Like Granactive Retinoid and Retinol, they have a great normalizing effect on the skin Love this It is a thin milky formula that applies and massages easily into skin. Lactic acid is the perfect choice for rough skin ![]() Lactic Acid 10% + HA is exfoliating and hydrating.Hyaluronic Acid 2%– Hydration is very important to ease stressed, textured skin.Which The Ordinary Products are good for Textural Irregularities? What causes it? The skin might become textured due to dryness, inflammation and/or blocked pores. How does skin look/feel like? Bumpy and rough, maybe dry and or red. What are textural irregularities? Texture occurs when the skin is not functioning properly.
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